NDI-101150

Lub npe tshuaj:

(S)-7-((6-(((dimethylamino)methyl)-5-(tetrahydrofuran-3-yl)pyridin-2-yl)amino)-4-(7-fluoroimidazo[1,2-a]pyridin- 3-yl) isoindolin-1-ib

SMILES Code:

O=C1NCC2=C(C3=CN=C4N3C=CC(F)=C4)C=CC(NC5=CC=C([C@@]6([H])COCC6)C(CN(C)C) = N5) = C21

InChi Code:

InChI=1S/C27H27FN6O2/c1-33(2)14-22-18(16-8-10-36-15-16)4-6-24(32-22)31-21-5-3-19( 20-12-30-27(35)26(20)2 1) 23-13-29-25-11-17(28)7-9-34(23)25/h3-7,9,11,13,16H,8,10,12,14-15H2,1- 2H3,(H,30,35)(H,31,32)/t16-/m1/s1

InChi Key:

QOMXZMCZISKNPU-MRXNPFEDSA-N

Lo lus tseem ceeb:

2628486-22-4; CAS: 2628486-22-4; CAS: 2628486-22-4; NDI-101150; NDI 101150; NDI 101150

Solubility: 

Cia:Qhuav, tsaus thiab ntawm 0 -4 C rau lub sijhawm luv (hnub mus rau lub lis piam) lossis -20 C rau lub sijhawm ntev (hli mus rau xyoo).

Nqe lus piav qhia:

NDI-101150 yog ib qho muaj zog thiab xaiv inhibitor ntawm HPK1 (hematopoietic progenitor cell kinase 1).

Hom phiaj: HPK1