Londamocitinib; JAK1-IN-7; AZD4604; JAC34RRR7S

Lub npe tshuaj:

(2R)-N-(3-{5-fluoro-2-[2-fluoro-3-(methanesulfonyl)anilino]pyrimidin-4-yl}-1H-indol-7-yl)-3-methoxy-2- (4-methylpiperazin-1-yl) propanamide

SMILES Code:

O=C(NC1=CC=CC2=C1NC=C2C3=NC(NC4=CC=CC(S(=O)(C)=O)=C4F)=NC=C3F)[C@H](N5CCN(C) 5) COC

InChi Code:

InChI=1S/C28H31F2N7O4S/c1-36-10-12-37(13-11-36)22(16-41-2)27(38)33-21-8-4-6-17-18(14- 31-26(17)21-25-19(29)15-32-28(35-25)34-20-7-5-9-23(24(20)30)42(3,39)40/ h4-9,14-15,22,31H,10-13,16H2,1-3H3,(H,33,38)(H,32,34,35)/t22-/m1/s1

InChi Key:

JNUZADQZHYFJGW-JOCHJYFZSA-N

Lo lus tseem ceeb:

2241039-81-4; CAS: 2241039-81-4; CAS: 2241039-81-4; Londamocitinib; JAK1-IN-7; AZD4604; AZD-4604; JAC34RRRR

Solubility: 

Cia:Qhuav, tsaus thiab ntawm 0 - 4 C rau lub sijhawm luv (hnub mus rau lub lis piam) lossis -20 C rau lub sijhawm ntev (hli mus rau xyoo).

Nqe lus piav qhia:

Londamocitinib (AZD4604) yog ib qho kev xaiv zoo JAK1 inhibitor.

Hom phiaj: JAK1