SJ-01

Inoa Kimia:

(E)-1-(3-(3,4,5-trimethoxyphenyl)acryloyl)-5,6-dihydropyridin-2(1H)-one

SMILES Code:

O=C1C=CCCN1C(/C=C/C2=CC(OC)=C(OC)C(OC)=C2)=O

Code InChi:

InChI=1S/C17H19NO5/c1-21-13-10-12(11-14(22-2)17(13)23-3)7-8-16(20)18-9-5-4-6- 15(18)19/h4,6-8,10-11H,5,9H2,1-3H3/b8-7+

Ki InChi:

VABYUUZNAVQNPG-BQYQJAHWSA-N

huaʻōlelo:

20069-09-4；CAS:20069-09-4；CAS:20069-09-4；Piperlongumine; Piplartine.

Hiki ke hoʻoheheʻe:Hiki ke hoʻoheheʻe ʻia ma DMSO

Waihona:Māloʻo, ʻeleʻele a ma 0 - 4 C no ka wā pōkole (nā lā i nā pule) a i ʻole -20 C no ka wā lōʻihi (mai nā mahina a hiki i nā makahiki).

wehewehe:

ʻO Piperlongumine, i kapa ʻia ʻo Piplartine, he alkaloid/amide olaola mai nā pepa, e like me ka pepa lōʻihi (Piper longum L. - Piperaceae). ʻO ka pepa lōʻihi kekahi o nā mea i hoʻohana nui ʻia i ka lāʻau Ayurvedic, i hoʻohana ʻia no ka mālama ʻana i nā maʻi he nui, me nā maʻi koko. ʻO nā hana lāʻau lapaʻau i hōʻike ʻia o ka piplartine he cytotoxic, genotoxic, antitumor, antiangiogenic, antimetastatic, antiplatelet aggregation, antinociceptive, anxiolytic, antidepressant, anti-atherosclerotic, antidiabetic, antibacterial, antifungal, leishmanicidal, trypanocidal, and activites. Ma waena o nā hopena pharmacological he nui o ka piplartine, ʻo kāna waiwai anticancer ka mea hoʻohiki loa.

Pahuhopu: ʻO Piperlongumine kahi alkaloid e kāohi ana i ka hoʻololi ʻana o nā myofibroblasts ma ke kāohi ʻana i ke ala hōʻailona erk1/2.