ʻO Sildenafil Citrate

Inoa Kimia:

5-(2-ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin- 7-hoʻokahi 2-hydroxypropane-1,2,3-tricarboxylate

SMILES Code:

"CCCC1=NN(C2=C1NC(=NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)CC(C(=O)O )C(CC(=O)O)(C(=O)O)O "

Code InChi:

InChI=1S/C22H30N6O4S.C6H8O7/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9- 18(16)32-6-2)33(30,31)28-12-10- 26(3)11-13-28;7-3(8)1-6(13,5(11)12)2-4(9)10/h8-9,14H,5-7,10 -13H2,1-4H3,(H,23,24,29);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

Ki InChi:

DEIYFTQMQPDXOT-UHFFFAOYSA-N

huaʻōlelo:

Sildenafil Citrate; UK 92480-10; UK-92,480-10; Revatio; VIAGRA; 171599-83-0; CAS: 171599-83-0; CAS: 171599-83-0

Hiki ke hoʻoheheʻe:Hiki ke hoʻoheheʻe ʻia ma DMSO

Waihona:0 - 4°C no ka wā pōkole (nā lā i nā pule), a i ʻole -20°C no ka wā lōʻihi (mau mahina)

wehewehe:

ʻO Sildenafil, ʻo Citrate kahi ʻano citrate o Sildenafil. ʻO Sildenafil kahi mea koho koho o PDE5 (type 5 cGMP phosphodiesterase) e hoʻopaʻa i ka hydrolysis o 3',5'-cyclic guanosine monophosphate (cGMP). Ma keʻano he mea pale PDE5, ua hōʻikeʻiaʻo Sildenafil e hoʻonui i ka neuro-, synapto- a me ka angiogenesis i nāʻanoʻiole o ka hahauʻana a ua hōʻikeʻia hoʻi he vasodilator māmā. Ua hōʻike pū ʻia ʻo Sildenafil e pale i ka hoʻokumu ʻana o ka ʻōpū liʻiliʻi indomethacin i hoʻokumu ʻia ma o kahi mīkini pili NO / cGMP.

Pahuhopu: PDE5