NK-3

CAT #	Inoa Huahana	wehewehe
CPD100768	Fezolinetant	ʻO Fezolinetant, ka mea i kapa ʻia ʻo ESN-364, ʻo ia ka Neurokinin-3 (NK-3) receptor antagonist i hoʻohana ʻia no ka hoʻohana ʻana i ke olakino wahine, a ke kūkulu ʻia nei no nā maʻi pili i ka sex-hormone e like me endometriosis, polycystic ovarian syndrome a me fibroids uterine. . Hiki i ka Fexolinetant ke hoʻololi i ka axis gonadal hypothalamic-pituitary me kahi hana koho i nā hormones pili i ka maʻi. Manaʻo ʻia e ʻoi aku ka ʻoi aku o ka hoʻomanawanui ma mua o nā huahana hoʻokūkū e kuhikuhi ana iā GnRH (Gonadotropin-releasing hormone).