| CAT # | Inoa Huahana | wehewehe |
| CPD3218 | BMS-955176 | ʻO GSK3532795, ka mea i ʻike ʻia ʻo BMS-955176, he mea ikaika, hoʻoikaika waha, ka lua o ka hanauna HIV-1 maturation inhibitor (MI) i holomua ma o ka pae IIb hoʻokolohua hoʻokolohua. Hoʻohui ʻo GSK3532795 i ka uhi ākea o nā maʻi maʻi polymorphic (EC50<15 nM e pili ana i kahi papa o nā polymorphisms maʻamau o ka 96.5% HIV-1 subtype B virus) me kahi ʻano pharmacokinetic maikaʻi i nā ʻano preclinical. |
