CAT # | Inoa Huahana | wehewehe |
CPD100391 | SHP394 | |
CPD100390 | SHP389 (kumu manuahi) | |
CPD3242 | RMC-4550 | ʻO RMC-4550 kahi mea hoʻopale SHP2 ikaika a koho. Ua ʻike ʻia ʻo RMC-4550 ma ke ʻano he pūhui mea hana kiʻekiʻe e aʻo ai i ke kuleana o SHP2 i ka biology tumor, i loko o ka vitro a i loko o ka vivo i nā rodents. ʻO SHP2 kahi node hōʻailona convergent a hiki ke kāohi ʻia o SHP2 i ka huli ʻana i nā hoʻololi i luna (RTK-driven) a me lalo (RAS-GTP dependent) i ke ala RAS-MAPK. |