LOXO-305;LY 3527727;Pirtobrutinib

Inoa Kimia:

(S)-5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-(1,1,1-trifluoropropan-2-yl)-1H-pyrazole-4- carboxamide

SMILES Code:

O=C(C1=C(N)N([C@@H](C)C(F)(F)F)N=C1C2=CC=C(CNC(C3=CC(F)=CC=C3OC )=O)C=C2)N

Code InChi:

InChI=1S/C22H21F4N5O3/c1-11(22(24,25)26)31-19(27)17(20(28)32)18(30-31)13-5-3-12(4-6- 13)10 -29-21(33)15-9-14(23)7-8-16(15)34-2/h3-9,11H,10,27H2,1-2H3,(H2,28,32)(H ,29,33)/t11-/m0/s1

Ki InChi:

FWZAWAUZXYCBKZ-NSHDSACASA-N

huaʻōlelo:

2101700-15-4；CAS:2101700-15-4；CAS:2101700-15-4；LOXO-305；LOXO 305；LOXO305；LY 3527727；LY-3527727；LY3527727；Pirtobrutinib

Hiki ke hoʻoheheʻe: 

Waihona:Māloʻo, ʻeleʻele a ma 0 - 4 C no ka wā pōkole (nā lā i nā pule) a i ʻole -20 C no ka wā lōʻihi (mai nā mahina a hiki i nā makahiki).

wehewehe:

ʻO Pirtobrutinib (LOXO-305) he mea koho nui loa a non covalent i ka hanauna hou BTK inhibitor hiki ke kāohi i nā ʻano hoʻololi hoʻololi BTK C481.

Pahuhopu: BTK