ʻEnelani

Inoa Kimia:

5-chloro-N-((2S,3R)-4-((3S,4R) -3,4-dihydroxypyrrolidin-1-yl)-3-hydroxy-4-oxo-1-phenylbutan-2-yl)- 1H-indole-2-carboxamide

SMILES Code:

O[C@H](C1)[C@@H](O)CN1C([C@H](O)[C@H](CC2=CC=CC=C2)NC(C3=CC4=C( N3)C=CC(Cl)=C4)=O)=O

Code InChi:

InChI=1S/C23H24ClN3O5/c24-15-6-7-16-14(9-15)10-18(25-16)22(31)26-17(8-13-4-2-1-3- 5-13)21(30)23(3 2)27-11-19(28)20(29)12-27/h1-7,9-10,17,19-21,25,28-30H,8,11-12H2,(H,26,31 )/t17-,19-,20+,21+/m0/s1

Ki InChi:

GDVRRZOORHCTAN-MJUUVYJYSA-N

huaʻōlelo:

ʻEnelani; CP-296; CP-368; CP-368,296; CP296; CP 296; CP-368296; CP368296; CP 368296

Hiki ke hoʻoheheʻe:DMSO

Waihona: 

wehewehe:

ʻO Ingliforib, ka mea i kapa ʻia ʻo CP-368296, he mea hoʻopaneʻe glycogen phosphorylase hou. Loaʻa iā Ingliforib nā waiwai antihyperglycemic a me ka cardioprotective. Hoʻopaʻa ʻo Ingliforib i ka glycogen phosphorylase, ka enzyme e kaupalena ʻia ana i ka glycogenolysis, no laila e pale ai i ka hoʻokuʻu ʻana o ka glucose-1 phosphate mai kahi mole glycogen i loko o ke ake. Hoʻopaʻa pū kēia mea hana i ka glycogen phosphorylase i loko o ka puʻuwai puʻuwai a hiki ke pale i ka puʻuwai mai ka hōʻeha ischemic myocardial ma o ka mālama ʻana i ka glycogen content a me ka hoʻomaikaʻi ʻana i ka hoʻohui glycolytic-oxidative.

ʻO ka pahuhopu: glycogen phosphorylase