Etoricoxib

Inoa Kimia:

5-Chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-2,3'-bipyridine

SMILES Code:

O=S(C1=CC=C(C2=CC(Cl)=CN=C2C3=CC=C(C)N=C3)C=C1)(C)=O

Code InChi:

InChI=1S/C18H15ClN2O2S/c1-12-3-4-14(10-20-12)18-17(9-15(19)11-21-18)13-5-7-16(8-6- 13)24(2,22)23/h3-11H,1-2H3

Ki InChi:

MNJVRJDLRVPLFE-UHFFFAOYSA-N

huaʻōlelo:

Etoricoxib, Arcoxia, L-791456, MK 0663, MK-0663, 202409-33-4

Hiki ke hoʻoheheʻe:Hiki ke hoʻoheheʻe ʻia ma DMSO

Waihona:0 - 4°C no ka wā pōkole (nā lā i nā pule), a i ʻole -20°C no ka wā lōʻihi (mau mahina)

wehewehe:

ʻO Etoricoxib kahi lāʻau anti-inflammatory synthetic, nonsteroidal anti-inflammatory (NSAID) me ka antipyretic, analgesic, a me nā waiwai antineoplastic. ʻO Etoricoxib e hoʻopaʻa pono a hoʻopaʻa i ka enzyme cyclooxygenase-2 (COX-2), ka hopena i ka hoʻololi ʻana o ka waika arachidonic i prostaglandins. ʻO ka hoʻopaʻa ʻana i ka COX-2 hiki ke hoʻoulu i ka apoptosis a keʻakeʻa i ka hoʻonui ʻana o nā cell tumor a me ka angiogenesis.

Pahuhopu: COX-2