Divarasib, GDC 6036
Huahana Huahana
Huahana Huahana
| Nui Puke | Loaʻa | Kumukuai (USD) |
| 0.1G | Loaʻa | 550 |
| 0.5G | Loaʻa | 860 |
| 1G | Loaʻa | 1250 |
Inoa Kimia:
1-((S)-4-(7-((R)-6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-((( S)-1-methylpyrrolidin-2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)prop-2-en-1-one
SMILES Code:
NC1=N[C@]([C@]2=C(C=C3C(N=C(N=C3N4[C@H](CN(CC4)C(C=C)=O)C)OC[ C@H]5N(CCC5)C)=C2F)Cl)=C(C(C)=C1)C(F)(F)F
Code InChi:
InChI=1S/C29H32ClF4N7O2/c1-5-21(42)40-9-10-41(16(3)13-40)27-18-12-19(30)22(26-23(29(32), 33)34)15(2)11-20 (35)36-26)24(31)25(18)37-28(38-27)43-14-17-7-6-8-39(17)4/h5,11-12,16-17H ,1,6-10,13-14H2,2-4H3,(H2,35,36)
Ki InChi:
ZRBPIAWWRPFDPY-UHFFFAOYSA-N
huaʻōlelo:
2417987-45-0;CAS:2417987-45-0;CAS:2417987-45-0;Divarasib;GDC 6036
Hiki ke hoʻoheheʻe:SolubilityE hoʻoholo ʻia
Waihona:Māloʻo, ʻeleʻele a ma 0 - 4 C no ka wā pōkole (nā lā i nā pule) a i ʻole -20 C no ka wā lōʻihi (mai nā mahina a hiki i nā makahiki).
wehewehe:
ʻO Divarasib (GDC-6036) he mea hoʻopaneʻe KRAS G12C me ka bioavailability oral a me ke koho.
Pahuhopu: KRAS G12C mea hoʻopaneʻe
