Chenodeoxycholic Acid

Inoa Kimia:

(R)-4-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl )ʻakika pentanoic

SMILES Code:

C[C@@H]([C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4( [H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)CCC(O)=O

Code InChi:

InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10- 8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15 +,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1

Ki InChi:

RUDATBOHQWOJDD-BSWAIDMHSA-N

huaʻōlelo:

474-25-9，CAS:474-25-9，CAS:474-25-9，Chenodeoxycholic Acid， Anthropodeoxycholic acid，Anthropodesoxycholic acid，CCRIS 2195，Chendol，Chenic acid; Chenix, ʻakika Chenodeoxycholic, ʻakika Chenodesoxycholic, Chenodiol, ʻakika Gallodesoxycholic, NSC 657949, Xenbilox

Hiki ke hoʻoheheʻe:Hiki ke hoʻoheheʻe ʻia i DMSO, ʻaʻole i ka wai

Waihona:Māloʻo, ʻeleʻele a ma 0 - 4 C no ka wā pōkole (nā lā i nā pule) a i ʻole -20 C no ka wā lōʻihi (mai nā mahina a hiki i nā makahiki)

wehewehe:

ʻO Chenodiol, ka mea i kapa ʻia ʻo Chenodeoxycholic Acid a me ka chenocholic acid, he waikawa bile. Loaʻa ia ma ke ʻano he mea hoʻoheheʻe keʻokeʻo hiki ʻole ke hoʻoheheʻe ʻia i ka wai akā hiki ke hoʻoheheʻe ʻia i loko o ka waiʻona a me ka waikawa acetic, me ka helu heheʻe ma 165-167 °C. Kapa ʻia nā paʻakai o kēia waikawa carboxylic he chenodeoxycholates. Ua hoʻohana ʻia ʻo Chenodeoxycholic acid ma ke ʻano he lāʻau lapaʻau e hoʻopau i nā pōhaku ʻōpū. Hiki ke hoʻohana ʻia ka waikawa Chenodeoxycholic i ka mālama ʻana i ka xanthomatosis cerebrotendineous. Ua hoʻāʻo ka hui biotechnology Australia ʻo Giaconda i kahi lāʻau lapaʻau no ka maʻi Hepatitis C e hui pū ai i ka chenodeoxycholic acid me bezafibrate.

Pahuhopu: Hoʻoulu ʻia ka mea hoʻokipa nuklea FXR