OTS964

OTS964
  • Suna:OTS964
  • Catalog No.:Saukewa: CPDB0996
  • Lambar CAS:1338545-07-5
  • Nauyin Kwayoyin Halitta:392.5
  • Tsarin Sinadarai:Saukewa: C23H24N2O2S
  • Don binciken kimiyya kawai, ba ga marasa lafiya ba.

    Cikakken Bayani

    Tags samfurin

    Girman Kunshin samuwa Farashin (USD)
    1g A Stock 1750
    Ƙarin Girman Girma Samu Magana Samu Magana

    Sunan Sinadari:

    (R) -9- (4- (1- (dimethylamino) propan-2-yl) phenyl) -8-hydroxy-6-methylthieno [2,3-c] quinolin-4 (5H) -daya

    Lambar SMILES:

    [H]Cl.O=C1NC2=C(C(C3=CC=C([C@@H](C)CN(C)C)C=C3=C(O)C=C2C)C4=C1SC =C4

    Lambar InChi:

    InChi=1S/C23H24N2O2S.ClH/c1-13-11-18(26)19(16-7-5-15(6-8-16)14(2)12-25(3)4)20-17- 9-10-28-22 (17)23 (27)24-21 (13)20;/h5-11,14,26H,12H2,1-4H3,(H,24,27);1H/t14-; /m0/s1

    InChi Key:

    YHPWOYBWUWSJDW-UQKRIMTDSA-N

    Mabuɗin kalma:

    OTS 964, OTS-964, OTS964, 1338545-07-5

    Solubility:Mai narkewa a cikin DMSO

    Ajiya:0 - 4 ° C na gajeren lokaci (kwanaki zuwa makonni), ko -20 ° C na dogon lokaci (watanni)

    Bayani:

    OTS964 shine mai hanawa na kisa mai kunna lymphokine T cell-based protein kinase (TOPK; IC50 = 28 nM). Musamman yana toshe cytokinesis, yana haifar da apoptosis, a cikin kewayon ƙwayoyin cutar kansa. OTS964 yana haifar da apoptosis na ƙwayoyin cutar kansar huhun ɗan adam a cikin xenografts na linzamin kwamfuta.

    manufa: TOPK


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