OTS964
Cikakken Bayani
Tags samfurin
Girman Kunshin | samuwa | Farashin (USD) |
1g | A Stock | 1750 |
Ƙarin Girman Girma | Samu Magana | Samu Magana |
Sunan Sinadari:
(R) -9- (4- (1- (dimethylamino) propan-2-yl) phenyl) -8-hydroxy-6-methylthieno [2,3-c] quinolin-4 (5H) -daya
Lambar SMILES:
[H]Cl.O=C1NC2=C(C(C3=CC=C([C@@H](C)CN(C)C)C=C3=C(O)C=C2C)C4=C1SC =C4
Lambar InChi:
InChi=1S/C23H24N2O2S.ClH/c1-13-11-18(26)19(16-7-5-15(6-8-16)14(2)12-25(3)4)20-17- 9-10-28-22 (17)23 (27)24-21 (13)20;/h5-11,14,26H,12H2,1-4H3,(H,24,27);1H/t14-; /m0/s1
InChi Key:
YHPWOYBWUWSJDW-UQKRIMTDSA-N
Mabuɗin kalma:
OTS 964, OTS-964, OTS964, 1338545-07-5
Solubility:Mai narkewa a cikin DMSO
Ajiya:0 - 4 ° C na gajeren lokaci (kwanaki zuwa makonni), ko -20 ° C na dogon lokaci (watanni)
Bayani:
OTS964 shine mai hanawa na kisa mai kunna lymphokine T cell-based protein kinase (TOPK; IC50 = 28 nM). Musamman yana toshe cytokinesis, yana haifar da apoptosis, a cikin kewayon ƙwayoyin cutar kansa. OTS964 yana haifar da apoptosis na ƙwayoyin cutar kansar huhun ɗan adam a cikin xenografts na linzamin kwamfuta.
manufa: TOPK