DEL-22379
Cikakken Bayani
Tags samfurin
| Girman Kunshin | samuwa | Farashin (USD) |
| 100mg | A Stock | 350 |
| 250mg | A Stock | 600 |
| 1g | A Stock | 1200 |
| Ƙarin Girman Girma | Samu Magana | Samu Magana |
Sunan Sinadari:
(Z) -N- (3- ((5-methoxy-1H-indol-3-yl) methylene) -2-oxoindolin-5-yl) -3- (piperidin-1-yl) propanamide.
Lambar SMILES:
O=C(NC1=CC2=C(NC(/C2=C/C3=CNC4=C3C=C(OC)C=C4)=O)C=C1)CCN5CCCCCC5
Lambar InChi:
InChi=1S/C26H28N4O3/c1-33-19-6-8-23-20(15-19)17(16-27-23)13-22-21-14-18(5-7-24(21) 29-26 (22)32)28-25 (31)9-12-30-10-3-2-4-11-30/h5-8,13-16,27H,2-4,9-12H2, 1H3, (H,28,31)(H,29,32)/b22-13+
InChi Key:
INQUULPXCZAKMS-LPYMAVHISA-N
Mabuɗin kalma:
DEL-22379, DEL22379, DEL 22379, 181223-80-3
Solubility:Mai narkewa a cikin DMSO
Ajiya:0 - 4 ° C na gajeren lokaci (kwanaki zuwa makonni), ko -20 ° C na dogon lokaci (watanni)
Bayani:
DEL-22379 mai ƙarfi ne kuma mai zaɓin ERK Dimerization inhibitor. DEL-22379 yana hana ERK Dimerization ba tare da shafar ERK phosphorylation ba, yana hana ƙwayar cuta ta hanyar RAS-ERK oncogenes. Kusan 50% na malignancies na mutum yana nuna alamar RAS-ERK mara izini; hana shi ingantacciyar dabara ce don shiga tsakani na antineoplastic.
manufa: ERK
