Ziftomenib;KO539
Sonraí Táirge
Clibeanna Táirge
| Méid Pacáiste | Infhaighteacht | Praghas (USD) |
| 0.1G | I Stoc | 650 |
| 0.5G | I Stoc | 970 |
| 1G | I Stoc | 1350 |
Ainm Cheimiceach:
(S)-4-Meitil-5-((4-((2-(meitilaimín)-6-(2,2,2-trífhluaraeitil)thieno(2,3-d)pirimidin-4-il)aimín)pipiridín -1-il)meitil)-1-(2-(4-(meitilsulfóin)píobairín-1-il)próipil)-1H-indole-2-carbónáitrile
Cód Smiles:
N#CC(N1C[C@H](N2CCN(S(=O)(C)=O)CC2)C)=CC3=C1C=CC(CN4CCC(NC5=C(C=C(CC(F)) (F)F)S6)C6=NC(NC)=N5)CC4)=C3C
Cód InChi:
InChI=1S/C33H42F3N9O2S2/c1-21(43-11-13-44(14-12-43)49(4,46)47) 19-45-25(18-37)15-27-22(2)23(5-6-29(27)45)20-42-9-7-24(8-10-42 )39-30-28-16-26(17-33(34,35)36)48-31(28)41-32(38-3)40-30/h5-6, 15-16,21,24H,7-14,17,19-20H2,1-4H3,(H2,38,39,40,41)/t21-/m0/s1
Eochair InChi:
BGGALFIXXQOTPY-NRFANRHFSA-N
Eochairfhocal:
2134675-36-6 ；CAS: 2134675-36-6； CAS: 2134675-36-6; KO539; KO 539; KO-539
Tuaslagthacht:Le cinneadh
Stóráil:Tirim, dorcha agus ag 0 - 4 C go gearrthéarmach (laethanta go seachtainí) nó -20 C go fadtéarmach (mí go blianta).
Cur síos:
Is inhibitor é Ziftomenib (KO-539) ar idirghníomhaíocht menin MLL le gníomhaíocht béil.
Sprioc: menin-MLL
