TNG462

Ainm Cheimiceach:

N-(6-aimín-5-eitilpyridin-3-il)-2-(5-meitil-2-(2-(1-meitilpiperidin-4-il)beansó[d]thiazol-5-il)piperidin-1 -il)-2-ocsaacetamide

Cód Smiles:

O=C(NC1=CC(CC)=C(N)N=C1)C(N1[C@@H](C2=CC=C3C(N=C(S3)C3CCN(C)CC3)=C2) CC[C@H](C)C1)=O

Cód InChi:

InChI=1S/C28H36N6O2S/c1-4-18-13-21(15-30-25(18)29)31-26(35)28(36)34-16-17(2)5-7-23( 34)20-6-8-24-22(14-20)32- 27(37-24)19-9-11-33(3)12-10-19/h6,8,13-15,17,19,23H,4-5,7,9-12,16H2,1- 3H3,(H2,29,30)(H,31,35)/t17-,23+/m0/s1

Eochair InChi:

DHAGMIPSRSPWSH-GAJHUEQPSA-N

Eochairfhocal:

2760483-96-1 CAS: 2760483-96-1 CAS: 2760483-96-1;TNG462

Tuaslagthacht: 

Stóráil:Tirim, dorcha agus ag 0 -4 C go gearrthéarmach (laethanta go seachtainí) nó -20 C go fadtéarmach (mí go blianta).

Cur síos:

Is inhibitor PRMT5 roghnach atá éifeachtach ó bhéal é TNG-462.

Sprioc: PRMT5