CCT 543; C220; Coscóir PRMT5

Ainm Cheimiceach:

(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,3-d]pirimidin-7-il)-5-[(R)-(4-clórafeinil)-hiodrocsaimeitil]ocsalainn-3,4 -diol

Cód Smiles:

O[C@H]1[C@H](N2C=CC3=C(N)N=CN=C32)O[C@H]([C@@H](C4=CC=C(Cl)C =C4)O)[C@H]1O

Cód InChi:

InChI=1S/C17H17ClN4O4/c18-9-3-1-8(2-4-9)11(23)14-12(24)13(25)17(26-14)22-6-5-10- 15(19)20-7-21-16(10)22/h1-7,11-14,17,23-25H,(H2,19,20,21)/t11-,12+,13-,14 -,17-/m1/s1

Eochair InChi:

ITEKIFMGFZAFPM-QFRSUPTLSA-N

Eochairfhocal:

1989620-03-2 CAS: 1989620-03-2 CAS: 1989620-03-2 ；PRT-543; PRT543; CCT 543; C220; inhibitor PRMT5; Coscóir PRMT5 C220

Tuaslagthacht: 

Stóráil:Tirim, dorcha agus ag 0 - 4 C go gearrthéarmach (laethanta go seachtainí) nó -20 C go fadtéarmach (mí go blianta).

Cur síos:

Is inhibitor PRMT5 éifeachtach roghnach agus gníomhach ó bhéal é PRMT5-IN-35 (Comhdhúil 87).

Sprioc: PRMT5