NX-2127

Ainm Cheimiceach:

3-((4-(1-((3R))-1-(2-(2,6-dé-ocsaipéiridin-3-il)-1,3-dé-ocsa-oisoindóil-5-il)pirrolidin-3-il)meitil) píobairídin-4-il)feinil)aimín)-5-(piperidin-1-il)pirazine-2-carboxamide

Cód Smiles:

O=C(C1=NC=C(N2CCCCC2)N=C1NC3=CC=C(C4CCN(C[C@@H]5CN(C6=CC7=C(C(N(C(CC8)C(NC8=O) )=O)C7=O)=O)C=C6)CC5)CC4)C=C3)N

Cód InChi:

InChI=1S/C39H45N9O5/c40-35(50)34-36(43-32(21-41-34)46-15-2-1-3-16-46)4 2-27-6-4-25(5-7-27)26-13-17-45(18-14-26)22-24-12-19-47(23-24)28-8-9- 29 -30(20-28)39(53)48(38(29)52)31-10-11-33(49)44-37(31)51/h4-9,20-21,24,2 6,31H,1-3,10-19,22-23H2,(H2,40,50)(H,42,43)(H,44,49,51)/t24-,31?/m1/s1

Eochair InChi:

XLWJWCMQMBVNSG-LZDHLTRGSA-N

Eochairfhocal:

2416131-46-7; CAS:2416131-46-7

Tuaslagthacht: 

Stóráil:Tirim, dorcha agus ag 0 - 4 C go gearrthéarmach (laethanta go seachtainí) nó -20 C go fadtéarmach (mí go blianta).

Cur síos:

Is inhibitor BTK éifeachtach ó bhéal é NX-2127.

Sprioc: BTK