NDI-101150

Ainm Cheimiceach:

(S)-7-((6-((démheitiolaimín)meitil)-5-(teitreahidreafhúráin-3-il)piridin-2-il)aimín)-4-(7-fluaraimínaigéin[1,2-a]piridín- 3-il)isoindolin-1-aon

Cód Smiles:

O=C1NCC2=C(C3=CN=C4N3C=CC(F)=C4)C=CC(NC5=CC=C([C@@]6([H])COCC6)C(CN(C)C) =N5)=C21

Cód InChi:

InChI=1S/C27H27FN6O2/c1-33(2)14-22-18(16-8-10-36-15-16)4-6-24(32-22)31-21-5-3-19( 20-12-30-27(35)26(20)21)23-13-29-25-11-17(28)7-9-34(23)25/h3-7,9,11,13, 16H,8,10,12,14-15H2,1-2H3,(H,30,35)(H,31,32)/t16-/m1/s1

Eochair InChi:

QOMXZMCZISKNPU-MRXNPFEDSA-N

Eochairfhocal:

2628486-22-4; CAS:2628486-22-4; CAS:2628486-22-4; NDI-101150; NDI 101150; NDI101150

Tuaslagthacht: 

Stóráil:Tirim, dorcha agus ag 0 -4 C go gearrthéarmach (laethanta go seachtainí) nó -20 C go fadtéarmach (mí go blianta).

Cur síos:

Tá NDI-101150 ina inhibitor potent agus roghnach de HPK1 (ceall hematopoietic progenitor kinase 1).

Sprioc: HPK1