Ifebemtinib, BI 853520

Ainm Cheimiceach:

4-[[4-[(2,3-Déhidrea-2-meitil-3-ocsa-1H-isoindól-4-il)ocsa]-5-(trífhluaramethyl)-2-pirimidinil]aimín]-2-fluara- 5-meitil-N-(1-meitil-4-piperidinil)beinsimíd

Cód Smiles:

O=C(NC1CCN(C)CC1)C2=CC(OC)=C(NC3=NC=C(C(F)(F)F)C(OC4=CC=CC(CN5C)=C4C5=O))= N3)C=C2F

Cód InChi:

InChI=1S/C28H28F4N6O4/c1-37-9-7-16(8-10-37)34-24(39)17-11-22(41-3)20(12-19(17)29)35- 27-33-13-18(28(30,31)32)25(36-27)42-21-6-4-5-15-14-38(2)26(40)23(15)21/ h4-6,11-13,16H,7-10,14H2,1-3H3,(H,34,39)(H,33,35,36)

Eochair InChi:

ULMMVBPTWVRPSI-UHFFFAOYSA-N

Eochairfhocal:

1227948-82-4 CAS: 1227948-82-4 CAS: 1227948-82-4 ；Ifebemtinib；BI 853520

Tuaslagthacht:Intuaslagtha i DMSO, ní in uisce

Stóráil:0 - 4 C don ghearrthéarma (laethanta go seachtainí), nó -20 C go fadtéarmach (míonna).

Cur síos:

Is inhibitor potent de kinase greamaitheacht fócasach (FAK) é Ifebemtinib (BI 853520) le gníomhaíocht ó bhéal.

Sprioc: Coscóir Láidir FAK