AZD0780;EX-A6975; laroprovstatum; laroprovstat

Ainm Cheimiceach:

6'-(((1S,3S)-3-((5-(défhluaramethocsa)pirimidin-2-il)aimín)cioclpentyl)aimín)-2H-[1,3'-bipiridin]-2-one

Cód Smiles:

O=C1N(C=CC=C1)C2=CN=C(N[C@H]3C[C@H](CC3)NC4=NC=C(OC(F)F)C=N4)C= C2

Cód InChi:

InChI=1S/C20H20F2N6O2/c21-19(22)30-16-11-24-20(25-12-16)27-14-5-4-13(9-14)26-17-7-6- 15(10 -23-17)28-8-2-1-3-18(28)29/h1-3,6-8,10-14,19H,4-5,9H2,(H,23,26)(H ,24,25,27)/t13-,14-/m0/s1

Eochair InChi:

NCHUWRLOTSAFFN-KBPBESRZSA-N

Eochairfhocal:

2455427-91-3; CAS:2455427-91-3; CAS:2455427-91-3; AZD0780; AZD0780; EX-A6975; EX-A 6975; EXA6975; laroprovstatum; laroprovstat

Tuaslagthacht: 

Stóráil:Tirim, dorcha agus ag 0 -4 C go gearrthéarmach (laethanta go seachtainí) nó -20 C go fadtéarmach (mí go blianta).

Cur síos:

Is cumaisc heitreamatacha é PCSK9-IN-12. Tá cleamhnas ceangailteach ag PCSK9-IN-12 do PCSK9 le luach Kd<200 nm. Is féidir PCSK9-IN-12 a úsáid chun staidéar a dhéanamh ar mheitibileacht colaistéaróil.

Sprioc: PCSK9