Tavapadon

Igama leMchiza:

I-1,5-dimethyl-6-[2-methyl-4-[3-(trifluoromethyl))pyridin-2-yl]oxyphenyl]pyrimidine-2,4-dione

Ikhowudi yoncumo:

O=C1NC(C(C)=C(C2=CC=C(OC3=NC=CC=C3C(F)(F)F)C=C2C)N1C)=O

Ikhowudi ye-InChi:

InChI=1S/C19H16F3N3O3/c1-10-9-12(28-17-14(19(20,21)22)5-4-8-23-17)6-7-13(10)15-11( 2)16(26)24-18(27)25(15)3/h4-9H,1-3H3,(H,24,26,27)

Isitshixo se-InChi:

AKQXQLUNFKDZBN-UHFFFAOYSA-N

Igama elingundoqo:

1643489-24-0;CAS:1643489-24-0;CAS:1643489-24-0;Tavapadon; PF-6649751; PF 6649751; PF6649751; I-CVL-751; I-CVL 751; CVL751

Ukunyibilika:Inyibilika kwi-DMSO

Ugcino:Yomile, emnyama kunye ne-0 - 4 C kwixesha elifutshane (iintsuku ukuya kwiiveki) okanye -20 C ixesha elide (iinyanga ukuya kwiminyaka).

Inkcazo:

I-Tavapadon, ekwabizwa ngokuba yi-PF-6649751 kunye ne-CVL-751, iyinxalenye ye-dopamine receptor agonist. Kunokuba luncedo kunyango lwe-Parkinson's disease kunye ne-Alzheimer's.

Ithagethi: I-Dopamine d1 / d5 i-receptor partial agonists