SJ-01

SJ-01
  • Igama:SJ-01
  • Inombolo yekhathalogu:CPD110955
  • Inombolo yeCAS:20069-09-4
  • Ubunzima beMolekyuli:317.34
  • Ifomula yemichiza:C17 H19 N O5
  • Kuphando lwenzululwazi kuphela, hayi izigulane.

    Iinkcukacha zeMveliso

    Iithegi zeMveliso

    Ubungakanani bePakethe Ubukho Ixabiso (USD)

    Igama leMchiza:

    (E)-1-(3-(3,4,5-trimethoxyphenyl)acryloyl)-5,6-dihydropyridin-2(1H)-enye

    Ikhowudi yoncumo:

    O=C1C=CCCN1C(/C=C/C2=CC(OC)=C(OC)C(OC)=C2)=O

    Ikhowudi ye-InChi:

    InChI=1S/C17H19NO5/c1-21-13-10-12(11-14(22-2)17(13)23-3)7-8-16(20)18-9-5-4-6- 15(18)19/h4,6-8,10-11H,5,9H2,1-3H3/b8-7+

    Isitshixo se-InChi:

    VABYUUZNAVQNPG-BQYQJAHWSA-N

    Igama elingundoqo:

    20069-09-4; CAS:20069-09-4; CAS: 20069-09-4;Piperlongumine; I-Piplatine.

    Ukunyibilika:Inyibilika kwi-DMSO

    Ugcino:Yomile, emnyama kunye ne-0 - 4 C kwixesha elifutshane (iintsuku ukuya kwiiveki) okanye -20 C ixesha elide (iinyanga ukuya kwiminyaka).

    Inkcazo:

    I-Piperlongumine, eyaziwa ngokuba yi-Piplartine, yi-alkaloid esebenzayo kwi-biologically/amide esuka kwipepile, njengesuka kwipepile ende (Piper longum L. - Piperaceae). I-pepper ende yenye yezona zinto zisetyenziswa kakhulu kwiyeza ze-Ayurvedic, ezisetyenziselwa ukunyanga izifo ezininzi, kuquka izicubu. Imisebenzi echaziweyo ye-pharmacological ye-piplatine ibandakanya i-cytotoxic, i-genotoxic, i-antitumor, i-antiangiogenic, i-antimetastatic, i-antiplatelet aggregation, i-antinociceptive, i-anxiolytic, i-anti-depressant, i-anti-atherosclerotic, i-antidiabetic, i-antibacterial, i-antifungal, i-leishmanicidal, i-trypanocistomidal, kunye nemisebenzi ye-schistomidal. Phakathi kweempembelelo ezininzi ze-pharmacological ze-piplatine, ipropati yayo ye-anticancer iyona nto ithembisayo.

    Ithagethi: I-Piperlongumine i-alkaloid inqanda ukuguqulwa kwe-myofibroblasts ngokuthintela i-erk1/2 indlela yokubonisa




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