SJ-01
Iinkcukacha zeMveliso
Iithegi zeMveliso
Ubungakanani bePakethe | Ubukho | Ixabiso (USD) |
Igama leMchiza:
(E)-1-(3-(3,4,5-trimethoxyphenyl)acryloyl)-5,6-dihydropyridin-2(1H)-enye
Ikhowudi yoncumo:
O=C1C=CCCN1C(/C=C/C2=CC(OC)=C(OC)C(OC)=C2)=O
Ikhowudi ye-InChi:
InChI=1S/C17H19NO5/c1-21-13-10-12(11-14(22-2)17(13)23-3)7-8-16(20)18-9-5-4-6- 15(18)19/h4,6-8,10-11H,5,9H2,1-3H3/b8-7+
Isitshixo se-InChi:
VABYUUZNAVQNPG-BQYQJAHWSA-N
Igama elingundoqo:
20069-09-4; CAS:20069-09-4; CAS: 20069-09-4;Piperlongumine; I-Piplatine.
Ukunyibilika:Inyibilika kwi-DMSO
Ugcino:Yomile, emnyama kunye ne-0 - 4 C kwixesha elifutshane (iintsuku ukuya kwiiveki) okanye -20 C ixesha elide (iinyanga ukuya kwiminyaka).
Inkcazo:
I-Piperlongumine, eyaziwa ngokuba yi-Piplartine, yi-alkaloid esebenzayo kwi-biologically/amide esuka kwipepile, njengesuka kwipepile ende (Piper longum L. - Piperaceae). I-pepper ende yenye yezona zinto zisetyenziswa kakhulu kwiyeza ze-Ayurvedic, ezisetyenziselwa ukunyanga izifo ezininzi, kuquka izicubu. Imisebenzi echaziweyo ye-pharmacological ye-piplatine ibandakanya i-cytotoxic, i-genotoxic, i-antitumor, i-antiangiogenic, i-antimetastatic, i-antiplatelet aggregation, i-antinociceptive, i-anxiolytic, i-anti-depressant, i-anti-atherosclerotic, i-antidiabetic, i-antibacterial, i-antifungal, i-leishmanicidal, i-trypanocistomidal, kunye nemisebenzi ye-schistomidal. Phakathi kweempembelelo ezininzi ze-pharmacological ze-piplatine, ipropati yayo ye-anticancer iyona nto ithembisayo.
Ithagethi: I-Piperlongumine i-alkaloid inqanda ukuguqulwa kwe-myofibroblasts ngokuthintela i-erk1/2 indlela yokubonisa