| CPD100768 | I-Fezolinetant | I-Fezolinetant, ekwabizwa ngokuba yi-ESN-364, yi-Neurokinin-3 (NK-3) ye-receptor antagonist eye yalungiselelwa ukusetyenziswa kwimpilo yabasetyhini, kwaye iphuhliselwa ukuphazamiseka okunxulumene ne-sex-hormone efana ne-endometriosis, i-polycystic ovarian syndrome kunye ne-uterine fibroids. . I-Fexolinetant ivumela ukuguqulwa kwe-hypothalamic-pituitary gonadal axis kunye nesenzo esikhethiweyo kwiihomoni ezifanelekileyo kwisifo. I-arhente kulindeleke ukuba ibe nokunyamezela okukhulu kuneemveliso ezikhuphisanayo ezijolise kwi-GnRH (i-Gonadotropin-releasing hormone). |
