MI

CAT # Igama lemveliso Inkcazo
CPD3218 BMS-955176 I-GSK3532795, ekwaziwa ngokuba yi-BMS-955176, inamandla, iyasebenza ngomlomo, isizukulwana sesibini i-HIV-1 maturation inhibitor (MI) eqhubele phambili kwisigaba se-IIb solingo lwezonyango. I-GSK3532795 idibanisa ukhuselo olubanzi lweentsholongwane zepolymorphic (EC50<15 nM ukuya kwiqela lepolymorphisms eqhelekileyo emele i-96.5% ye-HIV-1 subtype B yentsholongwane) eneprofayili ye-pharmacokinetic encomekayo kwiintlobo ze-preclinical.

Qhagamshelana nathi

Ukubuza

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