CAT # | Igama lemveliso | Inkcazo |
CPD100391 | SHP394 | |
CPD100390 | SHP389 (isiseko sasimahla) | |
CPD3242 | RMC-4550 | I-RMC-4550 yi-SHP2 inhibitor enamandla kwaye ekhethiweyo. I-RMC-4550 ichongiwe njengekhompawundi yesixhobo somgangatho ophezulu wokufunda indima ye-SHP2 kwi-tumor biology, zombini kwi-vitro nakwi-vivo kwiimpuku. I-SHP2 yindawo yomqondiso eguqukayo kunye nothintelo lwe-SHP2 luyasebenza ekujoliseni zombini phezulu (eqhutywa yi-RTK) kunye nasezantsi (i-RAS-GTP exhomekeke) kwiinguqu kwindlela ye-RAS-MAPK. |