Ifebemtinib,BI 853520

Igama leMchiza:

4- [[4- [(2,3-Dihydro-2-methyl-3-oxo-1H-isoindol-4-yl) oxy]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2-fluoro- I-5-methoxy-N-(1-methyl-4-piperidinyl) benzamide

Ikhowudi yoncumo:

O=C(NC1CCN(C)CC1)C2=CC(OC)=C(NC3=NC=C(C(F)(F)F)C(OC4=CC=CC(CN5C)=C4C5=O)= N3)C=C2F

Ikhowudi ye-InChi:

InChI=1S/C28H28F4N6O4/c1-37-9-7-16(8-10-37)34-24(39)17-11-22(41-3)20(12-19(17)29)35- 27-33-13-18(28(30,31)32)25(36-27)42-21-6-4-5-15-14-38(2)26(40)23(15)21/ h4-6,11-13,16H,7-10,14H2,1-3H3,(H,34,39)(H,33,35,36)

Isitshixo se-InChi:

ULMMVBPTWVRPSI-UHFFFAOYSA-N

Igama elingundoqo:

1227948-82-4;CAS:1227948-82-4;CAS:1227948-82-4;Ifebemtinib;BI 853520

Ukunyibilika:Inyibilika kwi-DMSO, hayi emanzini

Ugcino:0 - 4 C kwixesha elifutshane (iintsuku ukuya kwiiveki), okanye -20 C ixesha elide (iinyanga).

Inkcazo:

I-Ifebemtinib (BI 853520) yi-inhibitor enamandla ye-focal adhesion kinase (FAK) kunye nomsebenzi womlomo.

Ithagethi: FAK Strong Inhibitor