I-Chenodeoxycholic Acid

Igama leMchiza:

(R) -4-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl ) acid pentanoic

Ikhowudi yoncumo:

C[C@@H]([C@H]1CC[C@]]2([H])[C@]3([H])[C@H](O)C[C@]4( [H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)CCC(O)=O

Ikhowudi ye-InChi:

InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10- 8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15 +,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1

Isitshixo se-InChi:

RUDATBOHQWOJDD-BSWAIDMHSA-N

Igama elingundoqo:

474-25-9, CAS: 474-25-9, CAS: 474-25-9，Chenodeoxycholic Acid, Anthropodeoxycholic acid,Anthropodesoxycholic acid, CCRIS 2195,Chendol,chenic acid; Chenix, Chenodeoxycholic acid, Chenodesoxycholic acid, Chenodiol, Gallodesoxycholic acid, NSC 657949, Xenbilox

Ukunyibilika:Inyibilika kwi-DMSO, hayi emanzini

Ugcino:Yomile, emnyama kunye ne-0 - 4 C kwixesha elifutshane (iintsuku ukuya kwiiveki) okanye -20 C ixesha elide (iinyanga ukuya kwiminyaka)

Inkcazo:

I-Chenodiol, eyaziwa ngokuba yi-Chenodeoxycholic Acid kunye ne-chenocholic acid, i-bile acid. Kwenzeka njengento emhlophe eyikristale enganyibilikiyo emanzini kodwa inyibilika etywaleni nakwi-acetic acid, enendawo yokunyibilika kwi-165-167 °C. Iityuwa zale asidi ye-carboxylic zibizwa ngokuba yi-chenodeoxycholates. I-Chenodeoxycholic acid isetyenziswe njengonyango lonyango ukunyibilikisa amatye enyongo. I-Chenodeoxycholic acid ingasetyenziselwa unyango lwe-cerebrotendineous xanthomatosis. Inkampani yase-Australia ye-biotechnology i-Giaconda ivavanye unyango lwe-Hepatitis C usulelo oludibanisa i-chenodeoxycholic acid kunye ne-bezafibrate.

Ithagethi: Isamkeli senyukliya esisebenzayo iFXR