Ziftomenib;KO539

Lebitso:(S) -4-Methyl-5-((4-((2-(methylamino)-6-(2,2,2-trifluoroethyl)thieno(2,3-d)pyrimidin-4-yl)amino)piperidin -1-yl)methyl)-1-(2-(4-(methylsulfonyl)piperazin-1-yl)propyl)-1H-indole-2-carbonitrile

Nomoro ea lethathamo:CPD113642

Nomoro ea CAS:2134675-36-6

Boima ba Molek'hule:717.87

Foromo ea Lik'hemik'hale:C33 H42 F3 N9 O2 S2

Bakeng sa lipatlisiso tsa saense feela, eseng bakeng sa bakuli.

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Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Boholo ba Pakete	Ho fumaneha	Theko (USD)
0.1G	E teng thepeng e teng ka lebenkeleng	650
0.5G	E teng thepeng e teng ka lebenkeleng	970
1G	E teng thepeng e teng ka lebenkeleng	1350

Lebitso la lik'hemik'hale:

(S) -4-Methyl-5-((4-((2-(methylamino)-6-(2,2,2-trifluoroethyl)thieno(2,3-d)pyrimidin-4-yl)amino)piperidin -1-yl)methyl)-1-(2-(4-(methylsulfonyl)piperazin-1-yl)propyl)-1H-indole-2-carbonitrile

SMILES Khouto:

N#CC(N1C[C@@H](N2CCN(S(=O)(C)=O)CC2)C)=CC3=C1C=CC(CN4CCC(NC5=C(C=C(CC(F)) (F)F)S6)C6=NC(NC)=N5)CC4)=C3C

Khoutu ea InChi:

InChI=1S/C33H42F3N9O2S2/c1-21(43-11-13-44(14-12-43)49(4,46)47) 19-45-25(18-37)15-27-22(2)23(5-6-29(27)45)20-42-9-7-24(8-10-42 )39-30-28-16-26(17-33(34,35)36)48-31(28)41-32(38-3)40-30/h5-6, 15-16,21,24H,7-14,17,19-20H2,1-4H3,(H2,38,39,40,41)/t21-/m0/s1

InChi Key:

BGGALFIXXQOTPY-NRFANRHFSA-N

Keyword:

2134675-36-6;CAS:2134675-36-6;CAS:2134675-36-6;Ziftomenib; KO539; KO 539; KO-539

Sollubility:Ho ikemisetsa

Polokelo:E omme, e lefifi le ho 0 - 4 C bakeng sa nako e khutšoanyane (matsatsi ho isa ho libeke) kapa -20 C bakeng sa nako e telele (likhoeli ho isa ho lilemo).

Tlhaloso:

Ziftomenib (KO-539) ke inhibitor ea tšebelisano ea menin MLL le ts'ebetso ea molomo.

Sepheo: menin-MLL

E fetileng: 4,6-dichloro-5-fluoro-2-Methanesulfonyl-pyriMidine

E 'ngoe: N-Methyl-5-(piperazin-1-yl)picolinamide hydrochloride