Tavapadon

Lebitso la lik'hemik'hale:

1,5-dimethyl-6-[2-methyl-4-[3-(trifluoromethyl)pyridin-2-yl]oxyphenyl]pyrimidine-2,4-dione

SMILES Khouto:

O=C1NC(C(C)=C(C2=CC=C(OC3=NC=CC=C3C(F)(F)F)C=C2C)N1C)=O

Khoutu ea InChi:

InChI=1S/C19H16F3N3O3/c1-10-9-12(28-17-14(19(20,21)22)5-4-8-23-17 )6-7-13(10)15-11(2)16(26)24-18(27)25(15)3/h4-9H,1-3H3,(H,24,26,27)

InChi Key:

AKQXQLUNFKDZBN-UHFFFAOYSA-N

Keyword:

1643489-24-0;CAS:1643489-24-0;CAS:1643489-24-0;Tavapadon; PF-6649751; PF 6649751; PF6649751; CVL-751; CVL 751; CVL751

Sollubility:E qhibiliha ka DMSO

Polokelo:E omme, e lefifi le ho 0 - 4 C bakeng sa nako e khutšoanyane (matsatsi ho isa ho libeke) kapa -20 C bakeng sa nako e telele (likhoeli ho isa ho lilemo).

Tlhaloso:

Tavapadon, eo hape e tsejoang e le PF-6649751 le CVL-751, ke karolo ea dopamine receptor agonist. E ka ba molemo ho alafa lefu la Parkinson le Alzheimer's.

Sepheo: Dopamine d1/d5 receptor partial agonists