Quarfloxin

Quarfloxin
  • Lebitso:Quarfloxin
  • Nomoro ea lethathamo:CPD2205
  • Nomoro ea CAS:865311-47-3
  • Boima ba Molek'hule:604.67
  • Foromo ea Lik'hemik'hale:Setšoantšo sa C35H33FN6O3
  • Bakeng sa lipatlisiso tsa saense feela, eseng bakeng sa bakuli.

    Lintlha tsa Sehlahisoa

    Li-tag tsa Sehlahisoa

    Boholo ba Pakete Ho fumaneha Theko (USD)

    Lebitso la lik'hemik'hale:

    5-fluoro-N-(2-((S)-1-methylpyrrolidin-2-yl)ethyl)-3-oxo-6-((R)-3-(pyrazin-2-yl)pyrrolidin-1-yl )-3H-benzo[b]pyrido[3,2,1-kl]phenoxazine-2-carboxamide

    SMILES Khouto:

    FC1=C(N2CC[C@@H](C3=CN=CC=N3)C2)C(OC4=C5C=C6C(C=CC=C6)=C4)=C(N5C=C(C(NCC[ C@H]7N(C)CCC7)=O)C8=O)C8=C1

    Khoutu ea InChi:

    InChI=1S/C35H33FN6O3/c1-40-13-4-7-24(40)8-10-39-35(44)26-20-42-29-15-21-5-2-3-6- 22(21)16-30(29)45-34-31(42)25(33(26)43)17-27(36)32(34)41-14-9-23(19-41)28- 18-37-11-12-38-28/h2-3,5-6,11-12,15-18,20,23-24H,4,7-10,13-14,19H2,1H3,(H ,39,44)/t23-,24+/m1/s1

    InChi Key:

    WOQIDNWTQOYDLF-RPWUZVMVSA-N

    Keyword:

    CX 3543; CX-3543; CX 3543; Quarfloxacin

    Sollubility: 

    Polokelo: 

    Tlhaloso:

    Quarfloxin, eo hape e tsejoang e le Quarfloxacin le CX-3543, ke motsoako oa fluoroquinolone o nang le tšebetso ea antineoplastic. Quarfloxin e senya tšebelisano pakeng tsa protheine ea nucleolin le sebopeho sa G-quadruplex DNA template ea ribosomal DNA (rDNA), tšebelisano e mahlonoko bakeng sa rRNA biogenesis e fetisitsoeng ho feta lisele tsa kankere; Tšitiso ea DNA ena ea G-quadruplex: tšebelisano ea protheine ka har'a biogenesis e sa sebetseng ea rRNA e ka fella ka ho thibeloa ha ribosome synthesis le tumor cell apoptosis.

    Sepheo:


  • E fetileng:
  • E 'ngoe:

  • Lihlahisoa tse Amanang

    .
    Moqoqo oa Marang-rang oa WhatsApp!