PRT 543; C220; PRMT5 inhibitor

Lebitso:(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-[(R)-(4-chlorophenyl)-hydroxymethyl]oxolane-3,4 - diole

Nomoro ea lethathamo:CPDA600647

Nomoro ea CAS:1989620-03-2

Boima ba Molek'hule:376.79

Foromo ea Lik'hemik'hale:C17 H17 Cl N4 O4

Bakeng sa lipatlisiso tsa saense feela, eseng bakeng sa bakuli.

Re romelle lengolo-tsoibila Khoasolla joalo ka PDF

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Boholo ba Pakete	Ho fumaneha	Theko (USD)
0.1G	E teng thepeng e teng ka lebenkeleng	570
0.5G	E teng thepeng e teng ka lebenkeleng	850
1G	E teng thepeng e teng ka lebenkeleng	1350

Lebitso la lik'hemik'hale:

(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-[(R)-(4-chlorophenyl)-hydroxymethyl]oxolane-3,4 - diole

SMILES Khouto:

O[C@H]1[C@H](N2C=CC3=C(N)N=CN=C32)O[C@H]([C@@H](C4=CC=C(Cl)C =C4)O)[C@H]1O

Khoutu ea InChi:

InChI=1S/C17H17ClN4O4/c18-9-3-1-8(2-4-9)11(23)14-12(24)13(25)17(26-14)22-6-5-10- 15 (19)20-7-21-16(10)22/h1-7,11-14,17,23-25H,(H2,19,20,21)/t11-,12+,13-,14- ,17-/m1/s1

InChi Key:

ITEKIFMGFZAFPM-QFRSUPTLSA-N

Keyword:

1989620-03-2;CAS:1989620-03-2;CAS:1989620-03-2;PRT-543; PRT543; PRT 543; C220; PRMT5 inhibitor; PRMT5 inhibitor C220

Sollubility:

Polokelo:E omme, e lefifi le ho 0 - 4 C bakeng sa nako e khutšoanyane (matsatsi ho isa ho libeke) kapa -20 C bakeng sa nako e telele (likhoeli ho isa ho lilemo).

Tlhaloso:

PRMT5-IN-35 (Motsoako oa 87) ke PRMT5 inhibitor e sebetsang ka ho khetheha le e sebetsang ka molomo.

Sepheo: PRMT5

E fetileng: VPS34-IN1

E 'ngoe: (R) -(3aR,4R,6R,6aR)-6-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,2-dimethyltetrahydrofuro[3,4-d [1,3]dioxol-4-yl)(4-chlorophenyl)methanol