KATSE # | Lebitso la Sehlahiswa | Tlhaloso |
CPD101235 | diABZI STING agonist-1 trihydrochloride | diABZI STING agonist-1 (trihydrochloride) ke stimulator e khethollang ea liphatsa tsa lefutso tsa interferon (STING) receptor agonist, e nang le EC50s ea 130, 186 nM bakeng sa motho le mouse, ka ho latellana. |
CPD101234 | diABZI STING agonist-1 (Tautomerism) | diABZI STING agonist-1 Tautomerism (motsoako oa 3) ke ntho e susumetsang e khethollang ea liphatsa tsa lefutso tsa interferon (STING) receptor agonist, e nang le EC50s ea 130, 186 nM bakeng sa motho le mouse, ka ho latellana. |
CPD101233 | diABZI STING agonist-1 | diABZI STING agonist-1 ke ntho e susumetsang e khethollang ea liphatsa tsa lefutso tsa interferon (STING), tse nang le EC50s ea 130, 186 nM bakeng sa motho le mouse, ka ho latellana. |
CPD101232 | STING agonist-4 | STING agonist-4 ke stimulator ea Interferon Genes (STING) receptor agonist e nang le inhibitory constant (IC50) ea 20 nM. STING agonist-4 ke metsoako e 'meli e amanang le amidobenzimidazole (ABZI) e amanang le symmetry ho theha li-ABZI tse hokahantsoeng (diABZIs) tse nang le tlamo e matlafalitsoeng ho STING le tšebetso ea cellular. |
CPD101231 | STING agonist-3 | STING agonist-3, e ntšitsoeng ho patent WO2017175147A1 (mohlala 10), ke ntho e khethollang le e seng ea nucleotide e nyenyane ea molek'hule STING agonist e nang le pEC50 le pIC50 ea 7.5 le 9.5, ka ho latellana. STING agonist-3 e na le phello e tšoarellang ea anti-tumor le monyetla o moholo oa ho ntlafatsa kalafo ea mofets'e |