KATSE # | Lebitso la Sehlahiswa | Tlhaloso |
CPD100391 | SHP394 | |
CPD100390 | SHP389 (sebaka sa mahala) | |
CPD3242 | RMC-4550 | RMC-4550 ke SHP2 inhibitor e matla le e khethang. RMC-4550 e khethiloe e le motsoako oa lisebelisoa tsa boleng bo holimo ho ithuta karolo ea SHP2 ho baeloji ea tumor, in vitro le vivo ho litoeba. SHP2 ke node e feto-fetohang ea matšoao 'me thibelo ea SHP2 e sebetsa hantle ho lebiseng liphetoho tse fapaneng tsa hodimo (RTK-driven) le tlase (RAS-GTP itšetlehileng) tseleng ea RAS-MAPK. |