SHP2

KATSE # Lebitso la Sehlahiswa Tlhaloso
CPD100391 SHP394
CPD100390 SHP389 (sebaka sa mahala)
CPD3242 RMC-4550 RMC-4550 ke SHP2 inhibitor e matla le e khethang. RMC-4550 e khethiloe e le motsoako oa lisebelisoa tsa boleng bo holimo ho ithuta karolo ea SHP2 ho baeloji ea tumor, in vitro le vivo ho litoeba. SHP2 ke node e feto-fetohang ea matšoao 'me thibelo ea SHP2 e sebetsa hantle ho lebiseng liphetoho tse fapaneng tsa hodimo (RTK-driven) le tlase (RAS-GTP itšetlehileng) tseleng ea RAS-MAPK.
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