NST-628

Lebitso la lik'hemik'hale:

3-[[3-fluoro-2-(methylsulfamoylamino)pyridin-4-yl]methyl]-7-(3-fluoropyridin-2-yl)oxy-4-methylchromen-2-one

SMILES Khouto:

FC1=C(OC2=CC=C(C(C)=C(CC3=C(F)C(NS(NC)(=O)=O)=NC=C3)C(O4)=O)C4= C2)N=CC=C1

Khoutu ea InChi:

InChI=1S/C22H18F2N4O5S/c1-12-15-6-5-14(32-21-17(23)4-3-8-27-21)11-18(15)33-22(29 )16(12)10-13-7-9-26-20(19(13)24)28-34(30,31)25-2/h3-9,11,25H,10H2,1-2H3,( H,26,28)

InChi Key:

YQSZJOABXRROQR-UHFFFAOYSA-N

Keyword:

3002056-30-3;CAS:3002056-30-3;CAS:3002056-30-3;NST-628;NST628;NST 628

Sollubility: 

Polokelo:E omme, e lefifi le ho 0 -4 C bakeng sa nako e khutšoanyane (matsatsi ho isa ho libeke) kapa -20 C nako e telele (likhoeli ho isa ho lilemo).

Tlhaloso:

NST-628 ke MAPK pathway molecular gel e nang le thibelo ea mali-bokong, e ka thibelang phosphorylation ea RAF le ts'ebetso ea MEK.

Sepheo: RAF phosphorylation le MEK