LOXO-305;LY 3527727;Pirtobrutinib
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Lebitso la lik'hemik'hale:
(S) -5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-(1,1,1-trifluoropropan-2-yl)-1H-pyrazole-4- carboxamide
SMILES Khouto:
O=C(C1=C(N)N([C@@H](C)C(F)(F)F)N=C1C2=CC=C(CNC(C3=CC(F)=CC=C3OC )=O)C=C2)N
Khoutu ea InChi:
InChI=1S/C22H21F4N5O3/c1-11(22(24,25)26)31-19(27)17(20(28)32)18(30-31)13-5-3-12(4-6- 13)10-29-21(33)15-9-14(23)7-8-16(15)34-2/h3-9,11H,10,27H2,1-2H3,(H2,28,32 )(H,29,33)/t11-/m0/s1
InChi Key:
FWZAWAUZXYCBKZ-NSHDSACASA-N
Keyword:
2101700-15-4;CAS:2101700-15-4;CAS:2101700-15-4;LOXO-305;LOXO 305;LOXO305;LY 3527727;LY-3527727;LY3527727b;
Sollubility:
Polokelo:E omme, e lefifi le ho 0 - 4 C bakeng sa nako e khutšoanyane (matsatsi ho isa ho libeke) kapa -20 C bakeng sa nako e telele (likhoeli ho isa ho lilemo).
Tlhaloso:
Pirtobrutinib (LOXO-305) ke inhibitor ea BTK e khethang haholo ebile e sa sebetse hantle e ka thibelang liphetoho tse fapaneng tsa BTK C481.
Sepheo: BTK