Ifebemtinib, BI 853520

Lebitso la lik'hemik'hale:

4-[[4-[(2,3-Dihydro-2-methyl-3-oxo-1H-isoindol-4-yl) oxy] -5-(trifluoromethyl)-2-pyrimidinyl]amino] -2-fluoro- 5-methoxy-N-(1-methyl-4-piperidinyl)benzamide

SMILES Khouto:

O=C(NC1CCN(C)CC1)C2=CC(OC)=C(NC3=NC=C(C(F)(F)F)C(OC4=CC=CC(CN5C)=C4C5=O)= N3)C=C2F

Khoutu ea InChi:

InChI=1S/C28H28F4N6O4/c1-37-9-7-16(8-10-37)34-24(39)17-11-22(41-3)20(12-19(17)29)35- 27-33-13-18(28(30,3 1)32)25(36-27)42-21-6-4-5-15-14-38(2)26(40)23(15)21/h4-6,11-13,16H,7- 10,14H2,1-3H3,(H,34,39)(H,33,35,36)

InChi Key:

ULMMVBPTWVRPSI-UHFFFAOYSA-N

Keyword:

1227948-82-4;CAS:1227948-82-4;CAS:1227948-82-4;Ifebemtinib;BI 853520

Sollubility:E qhibiliha ka DMSO, eseng ka metsing

Polokelo:0 - 4 C bakeng sa nako e khutšoanyane (matsatsi ho isa ho libeke), kapa -20 C bakeng sa nako e telele (likhoeli).

Tlhaloso:

Ifebemtinib (BI 853520) ke inhibitor e matla ea focal adhesion kinase (FAK) e nang le ts'ebetso ea molomo.

Sepheo: FAK Strong Inhibitor