GDC6036; GDC6036 li-atropisomers
Lintlha tsa Sehlahisoa
Li-tag tsa Sehlahisoa
| Boholo ba Pakete | Ho fumaneha | Theko (USD) |
| 0.1G | E teng thepeng e teng ka lebenkeleng | 870 |
Lebitso la lik'hemik'hale:
2-Propen-1-one, 1-[(3S)-4-[7-[6-amino-4-methyl-3-(trifluoromethyl)-2-pyridinyl]-6-chloro-8-fluoro-2- [[(2S)-1-methyl-2-pyrrolidinyl]methoxy]-4-quinazolinyl]-3-methyl-1-piperazinyl]-
SMILES Khouto:
C=CC(N1C[C@H](C)N(C2=C3C=C(Cl)C(C4=NC(N)=CC(C)=C4C(F)(F)F)=C(F )C3=NC(OC[C@H]5N(C)CCC5)=N2)CC1)=O
Khoutu ea InChi:
InChI=1S/C29H32ClF4N7O2/c1-5-21(42)40-9-10-41(16(3)13-40)27-18-12-19(30)22(26-23(29(32,) 33)34)15(2)11-20(35)36-26)24(31)25(18)37-28(38-27)43-14-17-7-6-8-39(17) 4/h5,11-12,16-17H,1,6-10,13-14H2,2-4H3,(H2,35,36)/t16-,17-/m0/s1
InChi Key:
ZRBPIAWWRPFDPY-IRXDYDNUSA-N
Keyword:
2417917-17-8;CAS:2417917-17-8;CAS:2417917-17-8;GDC6036 atropisomers; GDC-6036; GDC 6036; GDC6036
Sollubility:
Polokelo:E omme, e lefifi le ho 0 - 4 C bakeng sa nako e khutšoanyane (matsatsi ho isa ho libeke) kapa -20 C bakeng sa nako e telele (likhoeli ho isa ho lilemo).
Tlhaloso:
GDC6036 anti rotation isomer e na le mefuta e 'meli ea li-isomer tsa GDC6036 anti rotation. GDC-6036, E tsejoang hape ka hore ke RG6330, ke inhibitor e fumanehang ka molomo, e sebetsang hantle haholo, ebile e khetha KRAS G12C inhibitor.
Sepheo: KRAS G12C
