BN104

Lebitso:(2-(6-(2-(4-cyclopropylpyrimidin-5-yl)-4-fluorophenoxy)-1,2,4-triazin-5-yl)-2,7-diazaspiro[3.5]nonan-7-yl )(1S,3aR,6aS) -octahydrocyclopenta[c]pyrrol-1-yl)methanone

Nomoro ea lethathamo:CPDP801669

Nomoro ea CAS:2938995-50-5

Boima ba Molek'hule:570.66

Foromo ea Lik'hemik'hale:C31 H35 F N8 O2

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Lebitso la lik'hemik'hale:

(2-(6-(2-(4-cyclopropylpyrimidin-5-yl)-4-fluorophenoxy)-1,2,4-triazin-5-yl)-2,7-diazaspiro[3.5]nonan-7-yl )(1S,3aR,6aS) -octahydrocyclopenta[c]pyrrol-1-yl)methanone

SMILES Khouto:

[H][C@@]12CCC[C@]1([H])[C@H](NC2)C(=O)N3CCC4(CN(C4)C5=C(OC6=CC=C(F) C=C6C7=CN=CN=C7C8CC8)N=NC=N5)CC3

Khoutu ea InChi:

1S/C31H35FN8O2/c32-21-6-7-25(23(12-21)24-14-33-17-35-26(24)19-4-5-19)42-29-28(36- 18-37-38-29)40-15-31(16-40)8-1 0-39(11-9-31)30(41)27-22-3-1-2-20(22)13-34-27/h6-7,12,14,17-20,22,27, 34H,1-5,8-11,13,15-16H2/t20-,22-,27-/m0/s1

InChi Key:

XDXAYPYOHXUEAM-CLHVYKLBSA-N

Keyword:

2938995-50-5;CAS:2938995-50-5;CAS:2938995-50-5;BN-104;BN104;BN 104

Sollubility:

Polokelo:E omme, e lefifi le ho 0 -4 C bakeng sa nako e khuts'oane (matsatsi ho isa ho libeke) kapa -20 C ka nako e telele (likhoeli ho isa ho lilemo)

Tlhaloso:

BN-104 (BNM-1192) e ka thibela tšebelisano ea Menin MLL mme e ka sebelisoa lipatlisisong tsa mofetše, joalo ka acute myeloid leukemia.

Sepheo: Menin-MLL

E fetileng: Cyclopenta[c]pyrrole-1,2(1H) -dicarboxylic acid, hexahydro-, 2-(1,1-dimethylethyl) 1-ethyl ester, (1S,3aR,6aS)

E 'ngoe: ethyl 2-((3bS,4aR) -5,5-difluoro-3-(trifluoromethyl) -3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol- 1-yl) acetate