AZD7507
Lintlha tsa Sehlahisoa
Li-tag tsa Sehlahisoa
| Boholo ba Pakete | Ho fumaneha | Theko (USD) |
| 100mg | e teng thepeng e teng ka lebenkeleng | Fumana quote |
| 500mg | e teng thepeng e teng ka lebenkeleng | Fumana quote |
| 1g | e teng thepeng e teng ka lebenkeleng | Fumana quote |
Lebitso la lik'hemik'hale:
4-(2-fluoro-4-methylanilino) -6-[4-(2-hydroxyethyl)piperazin-1-yl]-7-methoxycinnoline-3-carboxamide
SMILES Khouto:
O=C(C1=NN=C2C=C(OC)C(N3CCN(CCO)CC3)=CC2=C1NC4=CC=C(C)C=C4F)N
Khoutu ea InChi:
InChI=1S/C23H27FN6O3/c1-14-3-4-17(16(24)11-14)26-21-15-12-19(30-7-5-29(6-8-30)9- 10-31)20(33-2)13-18(15)27-28-22(21)23(25)32/h3-4,11-13,31H,5-10H2,1-2H3,(H2 ,25,32)(H,26,27)
InChi Key:
CPDGCAFPSYOTGO-UHFFFAOYSA-N
Keyword:
AZD7507; AZD-7507; AZD 7507
Sollubility:DMSO
Polokelo:
Tlhaloso:
AZD7507 ke CSF-1R inhibitor e matla le e khethang (32 nM cell activity), AZD7507 e nkoa e le motsoako o tšepisang kaha o ile oa boloka matla a lakatsehang le thepa ea molomo ea pharmacokinetic ea AZ683. Ho feta moo, thutong ea telemetry ho lintja tse fuoeng tekanyo e le 'ngoe ea molomo, ho ne ho se na chefo ea pelo, ha ho na ho phahama ha troponin ho amanang le phekolo,' me ha ho phetoho ho ECG.
Sepheo: CSF-1R
