Trelagliptin

Magaca Kiimikada:

(R) -2-((6- (3-aminopperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1 (2H) -yl) methyl) -4-fluorobenzonitrile succinate.

Koodhka dhoola cadeynta:

N#CC1=CC=C(F)C=C1CN(C(N2C)=O)C(N3C[C@H](N)CCC3)=CC2=O

Koodhka InChi:

InChi=1S/C18H20FN5O2/c1-22-17(25)8-16(23-6-2-3-15(21)11-23)24(18(22)26)1 0-13-7-14(19)5-4-12(13)9-20/h4-5,7-8,15H,2-3,6,10-11,21H2,1H3/t15-/m1 /s1

Furaha InChi:

IWYJYHUNXVAVAA-OAHLLOKOSA-N

Ereyga muhiimka ah:

Trelagliptin, Trelagliptin succinate, SYR-472, Zafatek, 865759-25-7, 1029877-94-8

Xalka:Ku milmay DMSO

Kaydinta:0 - 4°C muddo gaaban (maalmo ilaa toddobaadyo), ama -20°C muddo dheer (bilo).

Sharaxaad:

Trelagliptin, oo sidoo kale loo yaqaan SYR-472, waa firfircoonida dheer ee dipeptidyl peptidase-4 (DPP-4) inhibitor kaas oo ay soo saartay Takeda si loogu daweeyo nooca 2 ee sonkorowga (T2D). Daawaynta SYR-472-isbuuciiba hal mar waxay soo saartey kiliinikada iyo tirakoobka horumarka la taaban karo ee xakameynta glycemic ee bukaanada qaba nooca 2 ee sonkorowga. Si wanaagsan ayaa loo dulqaatay waxaana laga yaabaa inay u noqoto daawaynta cusub ee bukaanada qaba cudurkan. Trelagliptin (Zafatek(®)) ayaa Japan loogu oggolaaday daawaynta nooca 2aad ee sonkorowga mellitus (T2DM).

Ujeedka: DPP-4