OTS964
Faahfaahinta Alaabta
Tags Product
Cabbirka Xidhmada | Helitaanka | Qiimaha (USD) |
1g | In Stock | 1750kii |
Cabiro badan | Hel Xigasho | Hel Xigasho |
Magaca Kiimikada:
(R) -9- (4- (1- (dimethylamino) propan-2-yl) phenyl) -8-hydroxy-6-methylthieno [2,3-c] quinolin-4 (5H) -hal
Koodhka dhoola cadeynta:
[H]Cl.O=C1NC2=C(C(C3=CC=C([C@@H](C)CN(C)C)C=C3=C(O)C=C2C)C4=C1SC =C4
Koodhka InChi:
InChi=1S/C23H24N2O2S.ClH/c1-13-11-18(26)19(16-7-5-15(6-8-16)14(2)12-25(3)4)20-17- 9-10-28-22 (17)23 (27)24-21 (13)20;/h5-11,14,26H,12H2,1-4H3,(H,24,27);1H/t14-; /m0./s1
Furaha InChi:
YHPWOYBWUWSJDW-UQKRIMTDSA-N
Ereyga muhiimka ah:
OTS 964, OTS-964, OTS964, 1338545-07-5
Xalka:Ku milmay DMSO
Kaydinta:0 - 4°C muddo gaaban (maalmo ilaa toddobaadyo), ama -20°C muddo dheer (bilo)
Sharaxaad:
OTS964 waa horjooge-killer-killer-ka-firfircoon ee lymphokine-killer kinase protein unug (TOPK; IC50 = 28 nM). Waxay si gaar ah u xannibtaa cytokinesis, taasoo keenta apoptosis, oo ku jirta noocyo kala duwan oo unugyada kansarka ah. OTS964 waxay keentaa apoptosis ee unugyada kansarka sanbabada bini'aadamka ee jiirka xenografts.
Ujeedka: TOPK