Ertugliflozin

Magaca Kiimikada:

(1S,2S,3S,4R,5S)-5-(4-chloro-3- (4-ethoxybenzyl) phenyl)-1- (hydroxymethyl) -6,8-dioxabicyclo[3.2.1] octane-2,3 ,4-triol

Koodhka dhoola cadeynta:

"CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C34C(C(C(C(O3)(CO4)CO)O)O)O)Cl"

Koodhka InChi:

"InChi=1S/C22H25ClO7/c1-2-28-16-6-3-13(4-7-16)9-14-10-15(5-8-17(14)23)22-20(27) )18(25)19(26)21(11-24,30-22)12-29-22/h3-8,10,18-20,24-27H,2,9,11-12H2,1H3/t18 -,19-,20+,21-,22-/m0/s1"

Furaha InChi:

"MCIACXAZCBVDEE-CUUWFGFTSA-N"

Ereyga muhiimka ah:

Ertugliflozin, PF 04971729, MK-8835,1210344-57-2

Xalka:Ku milmay DMSO

Kaydinta:0 - 4°C muddo gaaban (maalmo ilaa toddobaadyo), ama -20°C muddo dheer (bilo).

Sharaxaad:

Ertugliflozin, oo sidoo kale loo yaqaan PF-04971729, waa horjooge awood leh oo door ah oo ka mid ah kooxiyaha gulukooska ku-tiirsan ee 2 iyo musharaxa bukaan-socodka ee daaweynta nooca 2 ee sonkorowga mellitus. Daraasada bukaan-socodka ayaa muujisay in Ertugliflozin (1-25 mg / maalintii) ay hagaajisay xakamaynta glycemic, miisaanka jidhka iyo cadaadiska dhiigga ee bukaannada T2DM si hoose loogu xakameynayo metformin, si fiicanna loo dulqaatay.

Ujeedka: SGLT-2