DEL-22379

DEL-22379
  • Magaca:DEL-22379
  • Lambarka buugga:CPDB3713
  • Lambarka CAS:181223-80-3
  • Miisaanka Molecular:444.55
  • Foomka Kiimikada:C26H28N4O3
  • Cilmi baaris cilmiyeed oo keliya, ma ahan bukaanka.

    Faahfaahinta Alaabta

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    Cabbirka Xidhmada Helitaanka Qiimaha (USD)
    100mg In Stock 350
    250mg In Stock 600
    1g In Stock 1200
    Cabiro badan Hel Xigasho Hel Xigasho

    Magaca Kiimikada:

    (Z)-N-(3-((5-methoxy-1H-indol-3-yl)methylene)-2-oxoindolin-5-yl)-3- (piperidin-1-yl) propanamide

    Koodhka dhoola cadeynta:

    O=C(NC1=CC2=C(NC(/C2=C/C3=CNC4=C3C=C(OC)C=C4)=O)C=C1)CCN5CCCCCC5

    Koodhka InChi:

    InChi=1S/C26H28N4O3/c1-33-19-6-8-23-20(15-19)17(16-27-23)13-22-21-14-18(5-7-24(21) 29-26 (22) 32)28-25(31)9-12-30-10-3-2-4-11-30/h5-8,13-16,27H,2-4,9-12H2,1H3,(H,28 ,31)(H,29,32)/b22-13+

    Furaha InChi:

    INQUULPXCZAKMS-LPYMAVHISA-N

    Ereyga muhiimka ah:

    DEL-22379, DEL22379, DEL 22379, 181223-80-3

    Xalka:Ku milmay DMSO

    Kaydinta:0 - 4°C muddo gaaban (maalmo ilaa toddobaadyo), ama -20°C muddo dheer (bilo)

    Sharaxaad:

    DEL-22379 waa ka hortag awood leh oo door ah ERK Dimerization. DEL-22379 waxay joojisaa Dimerization ERK iyada oo aan wax saameyn ah ku yeelan fosforyaalka ERK, waxay ka hortagtaa burooyinka oo ay wado RAS-ERK dariiqa oncogenes. Ku dhawaad ​​50% ee malignancies bini'aadamka ayaa muujinaya calaamad aan sharciyeysnayn RAS-ERK; Joojinta waa istaraatijiyad ansax ah oo loogu talagalay faragelinta antineoplastic.

    Ujeedka: ERK


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