Verucerfont
Product Detail
Khoom cim npe
Pob Loj | Muaj | Nqe (USD) |
100 mg | Hauv Tshuag | 700 |
Ntau qhov ntau thiab tsawg | Tau txais Quotes | Tau txais Quotes |
Lub npe tshuaj:
(S)-3-(4-methoxy-2-methylphenyl)-2,5-dimethyl-N-(1-(3-methyl-1,2,4-oxadiazol-5-yl)propyl)pyrazolo[1, 5-a] pyrimidin-7-amine
SMILES Code:
CC[C@H](NC1=CC(C)=NC2=C(C3=CC=C(OC)C=C3C)C(C)=NN12)C4=NC(C)=NO4
InChi Code:
InChI = 1S/C22H26N6O2/c1-7-18(22-24-15(5)27-30-22)25-19-11-13(3)23-21-20(14(4)26-28( 19) 21) 17-9-8-16(29-6)10-12(17)2/h8-11,18,25H,7H2,1-6H3/t18-/m0/s1
InChi Key:
VKHVAUKFLBBZFJ-SFHVURJKSA-N
Lo lus tseem ceeb:
Verucerfont, GSK561679, GSK 561679, GSK-561679, NBI77860, NBI 77860, NBI-77860, 885220-61-1
Solubility:Soluble hauv DMSO
Cia:0 - 4 ° C rau lub sijhawm luv (hnub mus rau lub lis piam), lossis -20 ° C rau lub sijhawm ntev (hli).
Nqe lus piav qhia:
"Verucerfont, tseem hu ua GSK561679 thiab NBI77860, yog CRF-1 antagonist. Verucerfont blocks CRH-1 receptor, thiab thiaj li txo ACTH tso tawm tom qab kev ntxhov siab ntev. Nws yog nyob rau hauv kev tshawb nrhiav raws li kev kho mob rau kev haus dej cawv, vim muaj kev ntxhov siab ntau zaus. ib qho tseem ceeb ntawm ob qho tib si kev txhim kho kev haus dej cawv thiab rov qab los ntawm kev haus cawv kom rov zoo Nws tau pom cov txiaj ntsig zoo hauv kev tshawb fawb tsiaj tab sis tsis tau sim hauv tib neeg.
Hom phiaj: CRF-1