R-268712

Lub npe tshuaj:

2-[4-[2-Fluoro-5-[3-(6-methylpyridine-2-yl)-1H-pyrazol-4-yl] phenyl] pyrazol-1-yl]ethanol

SMILES Code:

CC1=CC=CC(C2=NNC=C2C3=CC=C(F)C(C4=CN(CCO)N=C4)=C3)=N1

InChi Code:

InChI=1S/C20H18FN5O/c1-13-3-2-4-19(24-13)20-17(11-22-25-20)14-5-6-18(21)16(9-14) 15-10-23-26(12-15)7-8-27/h2-6,9-12,27H,7-8H2,1H3,(H,22,25)

InChi Key:

JQGOCCALXFSRHZ-UHFFFAOYSA-N

Lo lus tseem ceeb:

R-268712; R 268712; R268712

Solubility:DMSO

Cia: 

Nqe lus piav qhia:

R-268712 yog ib qho tshwj xeeb inhibitor ntawm activin receptor-zoo li kinase 5 (ALK5). Nws kuj yog ib qho kev hais lus nquag hloov pauv kev loj hlob zoo-β hom I receptor inhibitor.

Hom phiaj: ALK5