CAT # | Sunan samfur | Bayani |
Saukewa: CPD3218 | BMS-955176 | GSK3532795, wanda kuma aka sani da BMS-955176, mai ƙarfi ne, mai aiki da baki, mai hana cutar HIV-1 maturation na ƙarni na biyu (MI) wanda ya ci gaba ta hanyar gwaji na asibiti na IIb. GSK3532795 ya haɗu da faffadan ɗaukar hoto na ƙwayoyin cuta polymorphic (EC50<15 nM zuwa wani kwamiti na wakilin polymorphisms na gama gari na 96.5% HIV-1 subtype B virus) tare da ingantaccen bayanin pharmacokinetic a cikin nau'ikan preclinical. |