Luxdegalutamide; Saukewa: ARV-766
Cikakken Bayani
Tags samfurin
Girman Kunshin | samuwa | Farashin (USD) |
Sunan Sinadari:
4- (4- (1- (4- ((1r, 3r)) -3- (4-cyano-3-methoxyphenoxy) -2,2,4,4-tetramethylcyclobutyl) carbamoyl) phenyl) piperidin-4- yl) methyl) piperazin-1-yl)-N-((S) -2,6-dioxopiperidin-3-yl)-2-fluorobenzamide
Lambar SMILES:
CC1(C)[C@H](NC(C2=CC=C(N3CCC(CN4CCN(C5=CC(F))=C(N[C@H]6C(=O)NC(=O) CC6=O)C=C5)CC4)CC3)C=C2=O)C(C)(C)[C@H]1OC1=CC(OC)=C(C#N)C=C1
Lambar InChi:
InChi=1S/C45H54FN7O6/c1-44(2)42(45(3,4)43(44)59-33-12-8-30(26-47)37(25-33)5 8-5) 50-39 (55)29-6-9-31 (10-7-29) 52-18-16-28 (17-19-52) 27-51-20-22-53 (23- 21-51) 32-11-13-34 (35 (46)24-32)40 (56)48-36-14-15-38(54)49-41 (36)57/h6-13,24-25,28, 36,42-43H,14-23,27H2,1-5H3,(H,48,56)(H,50,55)(H,49,54,57)/t36-,42-,43-/m0 /s1
InChi Key:
RDPPBRKNBBXPNZ-FMPIRMQTSA-N
Mabuɗin kalma:
2750830-09-0;CAS:2750830-09-0;CAS:2750830-09-0;ARV766; ARV 766; ARV-766; GTPL12624; luxdegalutamide
Solubility:
Ajiya:Dry, duhu kuma a 0 - 4 C na gajeren lokaci (kwanaki zuwa makonni) ko -20 C na dogon lokaci (watanni zuwa shekaru).
Bayani:
Luxdegalutamide (ARV-766) ingantaccen furotin hydrolysis ne na baka wanda aka yi niyya na chimeric (PROTAC) wanda ke niyya mai karɓar mai karɓar androgen (AR), wanda zai iya ƙasƙantar da ƙwayoyin juriya na AR.
manufa: AR