Ingliforib
Cikakken Bayani
Tags samfurin
Girman Kunshin | samuwa | Farashin (USD) |
Sunan Sinadari:
5-chloro-N-((2S,3R)-4-((3S,4R)-3,4-dihydroxypyrrolidin-1-yl)-3-hydroxy-4-oxo-1-phenylbutan-2-yl)- 1H-indole-2-carboxamide
Lambar SMILES:
O[C@H](C1)[C@@H](O)CN1C([C@H](O)[C@H](CC2=CC=CC=C2)NC(C3=CC4=C( N3)C=CC(Cl)=C4)=O)=O
Lambar InChi:
InChi=1S/C23H24ClN3O5/c24-15-6-7-16-14(9-15)10-18(25-16)22(31)26-17(8-13-4-2-1-3- 5-13)21 (30)23 (32)27-11-19 (28)20 (29)12-27/h1-7,9-10,17,19-21,25,28-30H,8, 11-12H2,(H,26,31)/t17-,19-,20+,21+/m0/s1
InChi Key:
GVDRRZOORHCTAN-MJUUVYJYSA-N
Mabuɗin kalma:
Ingliforib; CP-296; CP-368; CP-368,296; CP296; CP 296; CP-368296; CP368296; Saukewa: CP368296
Solubility:DMSO
Ajiya:
Bayani:
Ingliforib, wanda kuma aka sani da CP-368296, sabon mai hana glycogen phosphorylase ne. Ingliforib yana da antihyperglycemic da Properties na zuciya. Ingliforib yana hana glycogen phosphorylase, ƙarancin ƙarancin enzyme a cikin glycogenolysis, don haka yana hana sakin glucose-1 phosphate daga ƙwayar glycogen a cikin hanta. Wannan wakili kuma yana hana glycogen phosphorylase a cikin tsokar zuciya kuma yana iya kare zuciya daga rauni na ischemic myocardial ta hanyar adana abun ciki na glycogen da haɓaka haɗin gwiwar glycolytic-oxidative.
Manufa: glycogen phosphorylase