Ifebemtinib, BI 853520

Sunan Sinadari:

4-[[4-[(2,3-Dihydro-2-methyl-3-oxo-1H-isoindol-4-yl) oxy]-5- (trifluoromethyl) -2-pyrimidinyl] amino]-2-fluoro- 5-methoxy-N- (1-methyl-4-piperidinyl) benzamide

Lambar SMILES:

O=C(NC1CCN(C)CC1)C2=CC(OC)=C(NC3=NC=C(C(F)(F)F)C(OC4=CC=CC(CN5C)=C4C5=O)= N3)C=C2F

Lambar InChi:

InChi=1S/C28H28F4N6O4/c1-37-9-7-16(8-10-37)34-24(39)17-11-22(41-3)20(12-19(17)29)35- 27-33-13-18(28(30,3 1)32)25(36-27)42-21-6-4-5-15-14-38(2)26(40)23(15)21/h4-6,11-13,16H,7- 10,14H2,1-3H3,(H,34,39)(H,33,35,36)

InChi Key:

ULMMVBPTWVRPSI-UHFFFAOYSA-N

Mabuɗin kalma:

1227948-82-4;CAS:1227948-82-4;CAS:1227948-82-4;Ifebemtinib;BI 853520

Solubility:Mai narkewa a cikin DMSO, ba cikin ruwa ba

Ajiya:0 - 4 C na gajeren lokaci (kwanaki zuwa makonni), ko -20 C na dogon lokaci (watanni).

Bayani:

Ifebemtinib (BI 853520) shine mai hanawa mai ƙarfi na adhesion kinase (FAK) tare da aikin baka.

Manufar: FAK Strong Inhibitor